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Matthew Brown

Parker Scholar

Biography

Matthew Brown is a Parker Scholar and a PhD candidate in the laboratory of Nina Bhardwaj, MD, PhD, at the Icahn School of Medicine at Mount Sinai (ISMMS). Prior to his doctoral work, he majored in cell biology and neuroscience at Rutgers University. He then pursued a master’s degree in clinical research at ISMMS, where he focused on mapping highly conserved and immunodominant SARS-CoV-2 T-cell epitopes following infection and vaccination. 

For his doctoral dissertation, Mr. Brown is studying shared frameshift (fs)–neoantigen expression during mismatch repair deficient (MMRd) cancer development, as well as examining how fs-specific T-cell exhaustion and suppression from innate immune cells promote escape from T-cell surveillance in MMRd cancer patients.

His broad research and professional interests are focused on understanding antigen-specific T-cell responses and immune evasion in cancer and viral infections to improve vaccine design and immunotherapeutic interventions.

View Mr. Brown’s YouTube Short.

Education & Training

  • 2021: Icahn School of Medicine at Mount Sinai, MS, Clinical Research
  • 2019: Rutgers University–New Brunswick, BS, Cell Biology and Neuroscience

Awards & Honors

  • 2023: Parker Scholar